Clopidogrel Versus Aspirin as Chronic Maintenance Antiplatelet Monotherapy in Patients After Percutaneous Coronary Intervention With Chronic Kidney Disease: A Post Hoc Analysis of the HOST-EXAM Trial.
Jeehoon KangSang-Hyeon ParkKyung Woo ParkBon-Kwon KooHuijin LeeMinju HanDoyeon HwangHan Mo YangSi-Hyuck KangWon-Yong ShinJu Hyeon OhYong Hoon KimTae-Ho ParkBum Soo KimJung-Kyu HanEun-Seok ShinHyo-Soo KimPublished in: Journal of the American Heart Association (2024)
During the chronic maintenance period after coronary stenting, the risk of thrombotic and bleeding events was significantly higher in patients with CKD compared with those without CKD. There was no statistical difference in the treatment effect of clopidogrel monotherapy in those with versus without CKD.
Keyphrases
- chronic kidney disease
- end stage renal disease
- percutaneous coronary intervention
- antiplatelet therapy
- acute coronary syndrome
- coronary artery disease
- combination therapy
- st segment elevation myocardial infarction
- st elevation myocardial infarction
- acute myocardial infarction
- coronary artery bypass grafting
- atrial fibrillation
- ejection fraction
- low dose
- open label
- peritoneal dialysis
- clinical trial
- cardiovascular events
- heart failure
- newly diagnosed
- phase iii
- left ventricular
- type diabetes
- aortic stenosis
- replacement therapy