Challenges in Harnessing Shared Within-Host Severe Acute Respiratory Syndrome Coronavirus 2 Variation for Transmission Inference.

Katharine S WalterEugene KimRenu VermaJonathan AltamiranoSean LearyYuan J CarringtonPrasanna JagannathanUpinder SinghMarisa K HolubarAruna SubramanianChaitan KhoslaYvonne MaldonadoJason R Andrews

Published in: Open forum infectious diseases (2023)

Shared within-host variation may augment the information in consensus sequences for predicting transmission linkages. Improving sensitivity and specificity of within-host variant identification will improve the informativeness of within-host variation.

Keyphrases

respiratory syndrome coronavirus
sars cov
coronavirus disease
machine learning
deep learning
structural basis