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Quantification of adherens junction disruption and contiguous paracellular protein leak in human lung endothelial cells under septic conditions.

Lefeng WangJustin ChungSean E GillSanjay Mehta
Published in: Microcirculation (New York, N.Y. : 1994) (2019)
These data support a mechanistic link between septic human lung MVEC VE-cadherin disruption and contiguous paracellular protein leak, and will permit more detailed assessment of individual cell-specific mechanisms of septic MVEC barrier dysfunction.
Keyphrases
  • acute kidney injury
  • endothelial cells
  • protein protein
  • single cell
  • binding protein
  • small molecule
  • machine learning
  • high glucose
  • vascular endothelial growth factor
  • cell migration
  • artificial intelligence