Measured weight loss as a precursor to cancer diagnosis: retrospective cohort analysis of 43 302 primary care patients.
Brian David NicholsonMatthew James ThompsonFrederick David Richard HobbsMatthew NguyenJulie MclellanBeverly Beth GreenJessica ChubakJason Lee OkePublished in: Journal of cachexia, sarcopenia and muscle (2022)
Weight loss is a sign of undiagnosed cancer regardless of the interval over which it occurs. Guidelines should resist giving an arbitrary cut-off for the interval of weight loss and focus on the percentage of weight loss and the patient's age. Future studies should focus on the association between diagnostic evaluation of weight change and risk of cancer mortality.
Keyphrases
- weight loss
- bariatric surgery
- papillary thyroid
- roux en y gastric bypass
- primary care
- gastric bypass
- squamous cell
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- glycemic control
- obese patients
- lymph node metastasis
- cardiovascular events
- coronary artery disease
- cardiovascular disease
- peritoneal dialysis
- case report
- prognostic factors
- young adults
- body mass index
- adipose tissue
- skeletal muscle
- general practice