Evaluating the progression to hypothyroidism in preconception euthyroid thyroid-peroxidase antibody positive women.

Sofia GillVersha CheedVictoria A H MortonDayna GillKristien BoelaertShiao ChanArri CoomarasamyRima K Dhillon-Smith

Published in: The Journal of clinical endocrinology and metabolism (2022)

Approximately 7% of euthyroid TPOAb positive women will develop hypothyroidism within 1 year preconception or in pregnancy. The risk is greater in women with higher baseline TSH concentrations. Prompt diagnosis and treatment of thyroid dysfunction ensures pregnancy outcomes are comparable to euthyroid individuals.

Keyphrases

pregnancy outcomes
pregnant women
replacement therapy
oxidative stress
polycystic ovary syndrome
adipose tissue
skeletal muscle
smoking cessation
insulin resistance
breast cancer risk