Impact of Mineralocorticoid Receptor Gene NR3C2 on the Prediction of Functional Classification of Left Ventricular Remodeling and Arrhythmia after Acute Myocardial Infarction.
Rima BraukylieneAli AldujeliAyman HaqLaurynas MaciuleviciusDarija JankauskaiteMartynas JurenasRamunas UnikasVytautas ZabielaVaiva LesauskaiteSandrita SimonyteDiana ZaliaduonytėPublished in: International journal of environmental research and public health (2022)
SNPs of the NR3C2 gene appear to correlate with better ventricular remodeling and a reduced rate of arrhythmias post-AMI, possibly by limiting the deleterious effects of cortisol on cardiomyocytes.
Keyphrases
- acute myocardial infarction
- left ventricular
- genome wide
- heart failure
- copy number
- percutaneous coronary intervention
- hypertrophic cardiomyopathy
- machine learning
- cardiac resynchronization therapy
- genome wide identification
- left atrial
- mitral valve
- deep learning
- dna methylation
- aortic stenosis
- catheter ablation
- acute coronary syndrome