Molecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumours display divergent genomic and transcriptomic profiles.
Michele SimboloSamantha BersaniCaterina VicentiniSergio V TaorminaChiara CiaparroneFabio BaganteBorislav RusevGiovanni CentonzeMarina MontresorMatteo BrunelliSerena PedronAndrea MafficiniGaetano PaolinoPaola MattioloSimone ConciMassimo MilioneAlfredo GuglielmiAndrea RuzzenenteAldo ScarpaClaudio LuchiniPublished in: Expert opinion on therapeutic targets (2021)
This study provides new insights into the molecular landscape and the actionable alterations of ECC. Our findings represent a step toward improved ECC molecular taxonomy and future therapeutic strategies for precision oncology.