Chemical Synthesis Enables the Configurational Determination of Myristriol, a Highly Oxygenated Phenylpropanoid from Myristica fragrans Houtt.

Wen-Wen XiaoHong-Lin ZhangChao-Fan WangYang ChenRui Zhan Dashan Li Li-Dong Shao

Published in: Chemistry & biodiversity (2023)

A new phenylpropanoid, myristriol (1), along with 11 known ones were isolated from the seed kernel of Myristica fragrans Houtt. Their chemical structures were clearly elucidated by extensive spectroscopic analysis. In which, the relative configuration of 1 was finally determined as erythro-1 by comparison the NMR data of two synthetic erythro- and threo-diastereoisomers with that of natural 1.

Keyphrases

high resolution
magnetic resonance
molecular docking
electronic health record
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solid state
molecularly imprinted
mass spectrometry
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molecular dynamics simulations