Antigen discovery by bioinformatics analysis and peptide microarray for the diagnosis of cystic echinococcosis.
Gherard Batisti BiffignandiAmbra VolaDavide SasseraSaeid Najafi-FardMaria Angeles Gomez MoralesEnrico BrunettiAntonella TeggiDelia GolettiLinda PetroneFrancesca TamarozziPublished in: PLoS neglected tropical diseases (2023)
Here we performed bioinformatics analysis and peptide microarray for antigen discovery, useful for the diagnosis of CE. Eight candidates were selected and validated. Reactivity to one peptide associated to CE but had suboptimal diagnostic accuracy. Importantly, the database developed in this study may be used to identify other antigenic candidates for CE diagnosis and follow-up.