Therapeutic potential of the metabolic modulator Metformin on osteosarcoma cancer stem-like cells.
Daniela I Paiva-OliveiraSara R Martins-NevesAntero José AbrunhosaCarlos Fontes RibeiroCélia M F GomesPublished in: Cancer chemotherapy and pharmacology (2017)
This preclinical study suggests that Metformin may be a potentially useful therapeutic agent and chemosensitizer of osteosarcoma stem-like cells to doxorubicin.