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New pathway ameliorating ulcerative colitis: focus on Roseburia intestinalis and the gut-brain axis.

Fenghua XuYi ChengGuangcong RuanLiqin FanYuting TianZhifeng XiaoDongfeng ChenYanling Wei
Published in: Therapeutic advances in gastroenterology (2021)
The administration of R. intestinalis contributes to restoration of the gut microbiota, promoting colon repair and the recovery of gastrointestinal function. These alterations are accompanied by the relief of depressive-like behaviors through a process modulated by the neuronal network and the regulation of inflammation by the gut-brain axis.
Keyphrases
  • ulcerative colitis
  • resting state
  • cerebral ischemia
  • white matter
  • functional connectivity
  • oxidative stress
  • multiple sclerosis
  • blood brain barrier