Critical role of the RpoE stress response pathway in polymyxin resistance of Escherichia coli.

Ximin ZengAtsushi HinenoyaZiqiang GuanFuzhou XuJun Lin

Published in: The Journal of antimicrobial chemotherapy (2023)

Inactivation of the important members of the RpoE regulon in polymyxin-resistant strains led to a drastic reduction in polymyxin MIC and an increase of lysophospholipids with no change in lipid A modifications.

Keyphrases

escherichia coli
gram negative
multidrug resistant
klebsiella pneumoniae
biofilm formation