The Effect of Cerium Oxide on Lung Tissue in Lower Extremity Ischemia Reperfusion Injury in Sevoflurane Administered Rats.

Aydin TuncayVolkan SivginAycan Ozdemirkan Saban Cem SezenHakan BoyunagaAysegül Kucuk Isın Gunes Mustafa Arslan

Published in: International journal of nanomedicine (2020)

We determined that the administration of 0.5 mg/kg dose of cerium oxide with sevoflurane reduces the oxidative stress and corrects IR-related damage in lung tissue. Our results show that the administration of cerium oxide before IR and the administration of sevoflurane during IR have a protective effect in rats.

Keyphrases

oxide nanoparticles
oxidative stress
dna damage
induced apoptosis
signaling pathway
heat stress