Involvement of TNF-α and IFN-γ in Inflammation-Mediated Cochlear Injury.

Sung K MoonJeong-Im WooDavid J Lim

Published in: The Annals of otology, rhinology, and laryngology (2019)

Taken together, these findings suggest the involvement of IFN-γ in the sensitization of cochlear cells to TNF-α cytotoxicity, which would enable us to better understand the complex mechanisms underlying inflammation-mediated cochlear injury.

Keyphrases

hearing loss
oxidative stress
induced apoptosis
rheumatoid arthritis
immune response
dendritic cells
cell cycle arrest
endoplasmic reticulum stress
cell death