Reproducibility of non-fasting plasma metabolomics measurements across processing delays.

Ying WangBrian D CarterSusan M GapsturMarjorie L McCulloughMia M GaudetVictoria L Stevens

Published in: Metabolomics : Official journal of the Metabolomic Society (2018)

Most metabolites measured by the UPLC-MS/MS platform show acceptable reproducibility up to 48-h processing delays. Metabolites of certain pathways need to be interpreted cautiously in relation to outcomes in epidemiologic studies with prolonged processing delays.

Keyphrases

ms ms
mass spectrometry
liquid chromatography tandem mass spectrometry
high throughput
insulin resistance
simultaneous determination
high resolution
skeletal muscle
case control