Impact Of ELN Risk Stratification, Induction Chemotherapy Regimens And Hematopoietic Stem Cell Transplantation On Outcomes In Hyperleukocytic Acute Myeloid Leukemia With Initial White Blood Cell Count More Than 100 × 109/L.
Shanglong FengLi ZhouXinhui ZhangBaolin TangXiaoyu ZhuHuilan LiuZimin SunChang-Cheng ZhengPublished in: Cancer management and research (2019)
This study suggest that hyperleukocytosis is an independent risk factor for AML patients, regardless of the risk stratification based on cytogenetic or molecular abnormalities. Age is the main factor influencing the prognosis of hyperleukocytic AML. The use of a standard IA regimen and HSCT can significantly improve the patient's prognosis.
Keyphrases
- acute myeloid leukemia
- allogeneic hematopoietic stem cell transplantation
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- stem cells
- case report
- squamous cell carcinoma
- type diabetes
- cell therapy
- bone marrow
- locally advanced
- skeletal muscle
- peripheral blood
- single molecule
- acute lymphoblastic leukemia
- weight loss
- rectal cancer
- mesenchymal stem cells