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18F-FDG PET-guided diffusion tractography reveals white matter abnormalities around the epileptic focus in medically refractory epilepsy: implications for epilepsy surgical evaluation.

Stefan E PoirierBenjamin Y M KwanMichael T JurkiewiczLina SamargandyDavid A StevenAna Suller-MartiVictor Lam Shin CheungAli R KhanJonathan RomsaFrank S PratoJorge G BurneoJonathan D ThiessenUdunna C Anazodo
Published in: European journal of hybrid imaging (2020)
We demonstrate here the utility of AI mapping in detecting the EF based on brain regions showing decreased FDG-PET activity and, when coupled with DTI, could be a powerful tool for detecting EF and assessing WM integrity in MRI-negative epilepsy. PET/DTI could be used to further enhance clinical decision-making in epilepsy surgery.
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