The polygenic risk for obsessive-compulsive disorder is associated with the personality trait harm avoidance.
Katharina BeyL WeinholdR GrützmannS HeinzelC KaufmannJulia KlawohnA RieselL LennertzM SchmidA RamirezN KathmannMichael WagnerPublished in: Acta psychiatrica Scandinavica (2020)
Our findings support the polygenic nature of OCD and further validate harm avoidance as a candidate endophenotype and diathesis of OCD.