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The polygenic risk for obsessive-compulsive disorder is associated with the personality trait harm avoidance.

Katharina BeyL WeinholdR GrützmannS HeinzelC KaufmannJulia KlawohnA RieselL LennertzM SchmidA RamirezN KathmannMichael Wagner
Published in: Acta psychiatrica Scandinavica (2020)
Our findings support the polygenic nature of OCD and further validate harm avoidance as a candidate endophenotype and diathesis of OCD.
Keyphrases
  • obsessive compulsive disorder
  • deep brain stimulation
  • genome wide