Effectiveness and Safety of Ustekinumab in Pediatric Ulcerative Colitis: A Multi-center Retrospective Study from the Pediatric IBD Porto Group of ESPGHAN.
Shlomi CohenHelena RolandsdotterKaija-Leena KolhoDan TurnerChristos TzivinikosMatteo BramuzzoGemma Pujol-MuncunillLuca ScaralloDarja UrlepFiras RinawiMaya GranotBen KangYlva LonguevilleMarta Velasco Rodríguez-BelvísYael WeintraubVíctor Manuel Navas-LópezAnat Yerushalmy-FelerPublished in: Paediatric drugs (2024)
Based on these findings, ustekinumab appears as an effective therapy for pediatric refractory UC and IBDU. The potential efficacy should be weighed against the risks of serious adverse events.