Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery.
Jingting WuHannah ChiShawn KokJason M W ChuaXi-Xiao HuangShipin ZhangShimin MahLi-Xin FooHui-Yee PehHui-Bing LeePhoebe TayCherie TongJasmine LadladCheryl H M TanNathanelle KhooDarius AwCheryl X Z ChongLeonard M L HoSharmini S SivarajahJialin NgWinson J H TanFung-Joon FooBin-Tean TehFrederick H KohPublished in: Annals of coloproctology (2023)
Sarcopenia, which is characterized by progressive and generalized loss of skeletal muscle mass and strength, has been well described to be associated with numerous poor postoperative outcomes, such as increased perioperative mortality, postoperative sepsis, prolonged length of stay, increased cost of care, decreased functional outcome, and poorer oncological outcomes in cancer surgery. Multimodal prehabilitation, as a concept that involves boosting and optimizing the preoperative condition of a patient prior to the upcoming stressors of a surgical procedure, has the purported benefits of reversing the effects of sarcopenia, shortening hospitalization, improving the rate of return to bowel activity, reducing the costs of hospitalization, and improving quality of life. This review aims to present the current literature surrounding the concept of sarcopenia, its implications pertaining to colorectal cancer and surgery, a summary of studied multimodal prehabilitation interventions, and potential future advances in the management of sarcopenia.
Keyphrases
- community dwelling
- skeletal muscle
- patients undergoing
- minimally invasive
- pain management
- coronary artery bypass
- physical activity
- systematic review
- intensive care unit
- multiple sclerosis
- acute kidney injury
- cardiac surgery
- squamous cell carcinoma
- rectal cancer
- cardiovascular events
- cardiovascular disease
- atrial fibrillation
- septic shock
- risk factors
- robot assisted
- surgical site infection
- adipose tissue
- quality improvement
- metabolic syndrome
- case report
- health insurance
- weight loss
- glycemic control