Characterization of lncRNA LINC00520 and functional polymorphisms associated with breast cancer susceptibility in Chinese Han population.

Qiaoyun GuoLinping XuRui PengYan MaYanli WangFeifei ChongMengmeng SongLiping Dai Chun-Hua Song

Published in: Cancer medicine (2020)

A genetic variant of rs8012083 in LINC00520 may be used as a biomarker for triple-negative BC after further evaluation of diagnostic tests. The genetic variant of LINC00520 was related to the susceptibility of BC, and rs12880540 might affect the corresponding mRNA expression of lncRNA LINC00520.

Keyphrases

long non coding rna
long noncoding rna
cell proliferation
copy number
gene expression
young adults
drug induced