Omeprazole Administration in Preterm Preeclampsia: a Randomized Controlled Trial to Study Its Effect on sFlt-1 (Soluble Fms-Like Tyrosine Kinase-1), PlGF (Placental Growth Factor), and ET-1 (Endothelin-1).

Rugina I NeumanMilan D BaarsLangeza SalehMichelle BroekhuizenDaan NieboerJérôme CornetteSam SchoenmakersMichel VerhoevenBirgit C P KochHenk RusscherSjoerd A A van den BergAnton H van den MeirackerWilly VisserAlexander H J Danser

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

Administration of omeprazole to women with confirmed preeclampsia does not alter their circulating levels of sFlt-1, PlGF, or ET-1, arguing against a role of this drug as a treatment for this syndrome.

Keyphrases

tyrosine kinase
growth factor
epidermal growth factor receptor
early onset
pregnancy outcomes
emergency department
low birth weight
gestational age
adverse drug