Intraoperative Tumor Localization of Early Gastric Cancers.
Chi-Young JeongKyung Won SeoJae-Seok MinPublished in: Journal of gastric cancer (2021)
Recently, endoscopic screening systems have enabled the diagnosis of gastric cancer in the early stages. Early gastric cancer (EGC) is typically characterized by a shallow invasion depth and small size, which can hinder localization of EGC tumors during laparoscopic surgery. Here, we review nine recently reported tumor localization methods for the laparoscopic resection of EGCs. Preoperative dye or blood tattooing has the disadvantage of spreading. Preoperative 3-dimensional computed tomography reconstruction is not performed in real time during laparoscopic gastrectomy. Thus, they are considered to have a low accuracy. Intraoperative portable abdominal radiography and intraoperative laparoscopic ultrasonography methods can provide real-time feedback, but these methods require expertise, and it can be difficult to define the clips in some gastric regions. Despite a few limitations, intraoperative gastrofibroscopy provides real-time feedback with high accuracy. The detection system using an endoscopic magnetic marking clip, fluorescent clip, and radio-frequency identification detection system clip is considered highly accurate and provides real-time feedback; we expect a commercial version of this setup to be available in the near future. However, there is not yet an easy method for accurate real-time detection. We hope that improved devices will soon be developed and used in clinical settings.
Keyphrases
- patients undergoing
- computed tomography
- robot assisted
- label free
- loop mediated isothermal amplification
- laparoscopic surgery
- endoscopic submucosal dissection
- real time pcr
- magnetic resonance imaging
- ultrasound guided
- high resolution
- contrast enhanced
- positron emission tomography
- quantum dots
- minimally invasive
- optical coherence tomography
- living cells
- sensitive detection
- molecularly imprinted
- low cost