Temporal trends of blood eosinophilia in severe uncontrolled CRSwNP treated with dupilumab: a real-life study.

Eugenio De Corso Claudio MontuoriSilvia BaroniRodolfo F MastrapasquaDavide P PorruLeandro Maria D'Auria Giuseppe D'AgostinoDaniele PenazziGabriele De MaioMaria E OnoriFrancesca SarloMarco Corbo'Jacopo Galli

Published in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2023)

In our series, we observed that an increase in AEC with different temporal trends may be observed in CRSwNP patients during the first year of treatment with dupilumab. In our series, eosinophilia is not correlated with a negative outcome of response to treatment or a risk of AEs.

Keyphrases

newly diagnosed
end stage renal disease
ejection fraction
chronic kidney disease
early onset
combination therapy
prognostic factors
patient reported outcomes
replacement therapy
smoking cessation