Miscarriage risk assessment: a bioinformatic approach to identifying candidate lethal genes and variants.

Mona AminbeidokhtiJia-Hua QuShweta BelurHakan CakmakEleni JaswaRuth B LathiMarina SirotaMichael P SnyderSvetlana A YatsenkoAleksandar Rajkovic

Published in: Human genetics (2024)

This study has identified a set of genes and variants potentially associated with lethality across different ethnic backgrounds. The variation of these genes across ethnic groups underscores the need for a comprehensive, pan-ethnic PGCS panel that includes genes related to miscarriage.

Keyphrases

genome wide
risk assessment
bioinformatics analysis
genome wide identification
copy number
genome wide analysis
dna methylation
heavy metals