Association of Dilated Perivascular Spaces With Cognitive Decline and Incident Dementia.
Matthew ParadiseJohn D CrawfordBen C P LamWei WenNicole A KochanSteve MakkarLaughlin DawesJulian N TrollorBrian DraperHenry BrodatyPerminder Singh SachdevPublished in: Neurology (2021)
Severe PVS pathology is a marker for increased risk of cognitive decline and dementia, independent of other small vessel disease markers. The differential cognitive associations for BG and CSO PVS may represent differences in their underlying pathology.