Single-neuron correlate of epilepsy-related cognitive deficits in visual recognition memory in right mesial temporal lobe.
Seung J LeeDanielle E BeamAndrea G P SchjetnanLynn K PaulNand ChandravadiaChrystal M ReedJeffrey M ChungIan B RossTaufik A ValianteAdam N MamelakUeli RutishauserPublished in: Epilepsia (2021)
Together, these findings show that single-cell responses can be used to assess the causal effects of local circuit disruption by an SOZ in the MTL, and establish a neural correlate of cognitive impairment due to epilepsy that can be used as a biomarker to assess the efficacy of novel treatments.