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Impact of cytomegalovirus infection prior to hematopoietic stem cell transplantation in children with inborn errors of immunity.

Teresa Del RosalCristian Quintana-OrtegaÀngela Deyà-MartínezPere Soler-PalacinWalter Alfredo Goycochea-ValdiviaNerea SalmónPérez-Martínez AntonioLaia AlsinaAndrea Martín-NaldaLaura AlonsoMarta Aboza GarciaLuz Yadira Bravo-GallegoLuis Ignacio González-GranadoAna Mendez-Echevarría
Published in: European journal of pediatrics (2022)
• In children with inborn errors of immunity and indication of HSCT, refractory cytomegalovirus disease is associated with a very high mortality rate, compared with non-infected children and those with non-refractory cytomegalovirus disease. • In patients with novel transplantation indications, the presence and treatment response of CMV infection should be considered to decide the best possible moment for HSCT.
Keyphrases
  • young adults
  • patient safety
  • acute myeloid leukemia
  • risk factors
  • cardiovascular events
  • coronary artery disease
  • cardiovascular disease
  • bone marrow
  • cell therapy
  • hematopoietic stem cell
  • quality improvement