Pressure-compacted and spider silk-reinforced fibrin demonstrates sufficient biomechanical stability as cardiac patch in vitro.

Dmitry BobylevMathias WilhelmiSkadi LauMelanie KlingenbergMarkus MlinaricElena PetenáFlorian HelmsThomas HasselAxel HaverichAlexander HorkeUlrike Böer

Published in: Journal of biomaterials applications (2021)

The combination of compacted fibrin matrices and spider silk cocoons may represent a feasible concept to generate stable and biocompatible cardiovascular patches with regenerative potential.

Keyphrases

tissue engineering
platelet rich plasma
stem cells
wound healing
ionic liquid
mesenchymal stem cells
human health
drug release
heart failure
cell therapy
finite element
finite element analysis
atrial fibrillation