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Selective Activation of Tumor Necrosis Factor Receptor II Induces Antiinflammatory Responses and Alleviates Experimental Arthritis.

Roman FischerMarcel ProskeMaëlle DuffeyHubert StanglGeorge F MartinezNathalie PetersAlexandra KraskeRainer H StraubJohn R BetheaRoland E KontermannKlaus Pfizenmaier
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2018)
Our findings support the use of TNFRII-selective therapeutics as an effective approach to the treatment of arthritic disease and possibly other inflammatory and autoimmune diseases.
Keyphrases
  • rheumatoid arthritis
  • oxidative stress
  • mouse model
  • binding protein