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Social dysfunction is transdiagnostically associated with default mode network dysconnectivity in schizophrenia and Alzheimer's disease.

Ilja M J SarisMoji AghajaniLianne M ReusPieter-Jelle VisserYolande PijnenburgNic J A van der WeeAmy C BilderbeckAndreea RaslescuAsad MalikMaarten MennesSanne KoopsCelso ArrangoJose Luis Ayuso-MateosGerard R DawsonHugh MarstonMartien J H KasBrenda W J H Penninxnull null
Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2021)
These findings pinpoint DMN connectional alterations as putative transdiagnostic endophenotypes for social dysfunction and could aid personalised care initiatives grounded in social behaviour.
Keyphrases
  • healthcare
  • mental health
  • oxidative stress
  • quality improvement
  • bipolar disorder
  • palliative care
  • cognitive decline
  • pain management
  • chronic pain
  • resting state