Social dysfunction is transdiagnostically associated with default mode network dysconnectivity in schizophrenia and Alzheimer's disease.

Ilja M J SarisMoji AghajaniLianne M ReusPieter-Jelle VisserYolande PijnenburgNic J A van der WeeAmy C BilderbeckAndreea RaslescuAsad MalikMaarten MennesSanne KoopsCelso ArrangoJose Luis Ayuso-MateosGerard R DawsonHugh MarstonMartien J H Kas Brenda W J H Penninxnull null

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2021)

These findings pinpoint DMN connectional alterations as putative transdiagnostic endophenotypes for social dysfunction and could aid personalised care initiatives grounded in social behaviour.

Keyphrases

healthcare
mental health
oxidative stress
quality improvement
bipolar disorder
palliative care
cognitive decline
pain management
chronic pain
resting state