Hippocampal temporal dynamics and spatial heterogeneity unveil vulnerability markers in the offspring of bipolar patients.
Luigi Francesco SaccaroFarnaz DelavariDimitri Van De VilleCamille PiguetPublished in: Bipolar disorders (2024)
Overall, we observed alterations of large-scale functional brain networks associated with decreased cognitive control flexibility and disrupted somatomotor, saliency, and emotion processing in BD. Interestingly, BDoff presented an intermediate phenotype between BD and HC, suggesting that dFC of hippocampal subregions might represent a marker of vulnerability to BD.
Keyphrases
- end stage renal disease
- climate change
- cerebral ischemia
- newly diagnosed
- ejection fraction
- chronic kidney disease
- resting state
- prognostic factors
- depressive symptoms
- autism spectrum disorder
- peritoneal dialysis
- bipolar disorder
- single cell
- multiple sclerosis
- type diabetes
- functional connectivity
- white matter
- metabolic syndrome
- blood brain barrier
- patient reported outcomes
- subarachnoid hemorrhage
- skeletal muscle
- temporal lobe epilepsy