Time of Liver Function Abnormal Identification on Prediction of the Risk of Anti-tuberculosis-induced Liver Injury.

Deliang Huang Jinghan PengLin LeiYuanyuan ChenZhibing ZhuQingxian CaiYongcong DengJun Chen

Published in: Journal of clinical and translational hepatology (2022)

The time to identification of LFT was positively correlated with DILI, liver failure, and anti-TB drug resistance. The risk of DILI and liver failure was significantly increased in the late identification group with abnormal LFT identified after 8 weeks compared with 4 and 8 weeks. Early monitoring of LFT is recommended for patients without the high-risk factor of DILI after anti-TB treatment is initiated.

Keyphrases

liver failure
hepatitis b virus
drug induced
mycobacterium tuberculosis
end stage renal disease
bioinformatics analysis
newly diagnosed
risk factors
prognostic factors
peritoneal dialysis
gestational age
pulmonary tuberculosis
patient reported
preterm birth