IL-17A haplotype confers susceptibility to systemic lupus erythematosus but not to rheumatoid arthritis in Mexican patients.

Isela Montúfar-RoblesRosa E Barbosa-CobosIsidro Alemán-ÁvilaJulián Ramírez Bello

Published in: International journal of rheumatic diseases (2018)

These results confirm that the IL-17A -737T/C, -444A/G, -197G/A, and -121G/A SNPs are not risk factors for RA, but the IL-17A TAGA haplotype is a risk factor for SLE. This is the first report to document an association between IL-17A and SLE susceptibility in adults.

Keyphrases

systemic lupus erythematosus
disease activity
rheumatoid arthritis
end stage renal disease
ejection fraction
ankylosing spondylitis
newly diagnosed
chronic kidney disease
prognostic factors
interstitial lung disease