IL-17A haplotype confers susceptibility to systemic lupus erythematosus but not to rheumatoid arthritis in Mexican patients.
Isela Montúfar-RoblesRosa E Barbosa-CobosIsidro Alemán-ÁvilaJulián Ramírez BelloPublished in: International journal of rheumatic diseases (2018)
These results confirm that the IL-17A -737T/C, -444A/G, -197G/A, and -121G/A SNPs are not risk factors for RA, but the IL-17A TAGA haplotype is a risk factor for SLE. This is the first report to document an association between IL-17A and SLE susceptibility in adults.