HCC incidence after hepatitis C cure among patients with advanced fibrosis or cirrhosis: A meta-analysis.
Ian LockartMalcolm G H YeoBehzad HajarizadehGregory J DoreThomas BergPublished in: Hepatology (Baltimore, Md.) (2022)
Among patients with cirrhosis, the incidence of HCC decreases over time after HCV cure and is lowest in patients with younger age and compensated cirrhosis. The substantially lower incidence in F3 fibrosis is below the recommended threshold for cost-effective screening. The results should encourage the development of validated predictive models that better identify at-risk individuals, especially among patients with F3 fibrosis.