Early but not late convalescent plasma is associated with better survival in moderate-to-severe COVID-19.
Neima BriggsMichael V GormallyFangyong LiSabrina L BrowningMiriam M TreggiariAlyssa MorrisonMaudry Laurent-RolleYanhong DengJeanne E HendricksonChristopher A TormeyMahalia S DesruisseauxPublished in: PloS one (2021)
Early administration of CCP improves outcomes in patients with moderate-to-severe COVID-19, while improvement was not observed with late CCP administration. The importance of timing of administration should be addressed in specifically designed trials.