Electrostatic forces drive poleward chromosome motions at kinetochores.

Published in: Cell division (2016)

We propose here that implicating Ndc80/Hec1 as a bound volume positive charge distribution in electrostatic generation of poleward force at kinetochores is most consistent with a wide range of experimental observations on mitotic motions, including polar production of poleward force and chromosome congression.

Keyphrases

single molecule
copy number
molecular dynamics simulations
cell cycle
ionic liquid
cell proliferation