Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes.
Helena OlbertovaKarla PlevovaSarka PavlovaJitka MalcikovaJana KotaskovaKamila StranskaMichaela SpunarovaMartin TrbusekVeronika NavrkalovaBarbara DvorackovaNikola TomKarol PalMarie JarosovaYvona BrychtovaAnna PanovskaMichael DoubekSarka PospisilovaPublished in: BMC cancer (2022)
Our study revealed that changes of telomere length reflect evolution in leukemic subclone proportion, and are associated with specific clinico-biological features of the explored cohort.
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