Can earlier biomarker measurements explain a treatment effect on diabetes incidence? A robust comparison of five surrogate markers.

Layla ParastLu TianTianxi CaiLatha P Palaniappan

Published in: BMJ open diabetes research & care (2023)

These data suggest that, of the five examined surrogate markers, glucose and HOMA-IR were the superior surrogate markers in terms of PTE, compared with 2-hour glucose, HbA1c, and TyG index.

Keyphrases

type diabetes
blood glucose
cardiovascular disease
blood pressure
electronic health record
big data
glycemic control
machine learning
metabolic syndrome
adipose tissue
insulin resistance