Organoid technology for personalized pancreatic cancer therapy.
Axel BengtssonRoland AnderssonJonas RahmKarthik GangannaBodil AnderssonDaniel AnsariPublished in: Cellular oncology (Dordrecht) (2021)
This review attempts to outline the most important challenges that remain in exploiting organoid platforms for drug discovery and clinical applications. Some of these challenges may be overcome by novel methods that are under investigation, such as 3D bioprinting systems, microfluidic systems, optical metabolic imaging and liquid handling robotics. We also propose an optimized organoid workflow inspired by all technical solutions we have presented.