Safety Assessment of Liver Injury with Quetiapine Fumarate XR Management in Very Heavy Drinking Alcohol-Dependent Patients.
Vatsalya VatsalyaAkash PandeyMelanie L SchwandtMatthew C CaveShirish S BarveVijay A RamchandaniCraig J McClainPublished in: Clinical drug investigation (2017)
Quetiapine XR did not show any significant exacerbation of liver injury in very heavy drinking alcohol-dependent patients with pre-existing liver injury. Frequency and severity of new liver injury cases in quetiapine XR-treated patients without any pre-existing liver injury was also low. Study findings support medical management of AD patients with heavy drinking profile using quetiapine XR formulation.