MicroRNA-326-5p enhances therapeutic potential of endothelial progenitor cells for myocardial infarction.

Xiaoting LiXiang XueYuejun SunLei ChenTing ZhaoWentao YangYongbing ChenZhiwei Zhang

Published in: Stem cell research & therapy (2019)

miR-326-5p significantly enhanced the angiogenic capacity of EPCs. Transplantation of miR-326-5p-overexpressing EPCs improved cardiac function for AMI therapy, which can be a novel strategy for enhancing therapeutic angiogenesis in ischemic heart diseases.

Keyphrases

endothelial cells
heart failure
acute myocardial infarction
left ventricular
cell therapy
vascular endothelial growth factor
atrial fibrillation
stem cells
mesenchymal stem cells
cerebral ischemia
brain injury
percutaneous coronary intervention
subarachnoid hemorrhage