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Inhibiting IGF1R-mediated Survival Signaling in Head and Neck Cancer with the Peptidomimetic SSTN IGF1R .

Noah A StuevenDeannaLee M BeauvaisRong HuRandall J KimpleAlan C Rapraeger
Published in: Cancer research communications (2023)
. A corresponding blockade in PDX growth in the presence of this inhibitor demonstrates that therapies designed to target this mechanism will likely offer promising outcomes for patients with head and neck cancer.
Keyphrases
  • pi k akt
  • growth hormone
  • signaling pathway
  • binding protein
  • cell proliferation
  • metabolic syndrome
  • adipose tissue
  • type diabetes
  • insulin resistance
  • glycemic control