Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure.
Rebecca L HullRonald L GibsonSharon McNamaraGail H DeutschCorinne L FlignerCharles W FrevertBonnie W RamseySrinath SandaPublished in: Diabetes care (2018)
These findings reveal novel molecular pathways and therapeutic targets underlying islet pathology in CF subjects and may be important in developing new approaches to treat CFRD.