PLCG2 and IFNAR1: The Potential Biomarkers Mediated by Immune Infiltration and Osteoclast Differentiation of Ankylosing Spondylitis in the Peripheral Blood.

Bo Han Qiaobo XieWeishi LiangPeng YinXianjun Qu Yong Hai

Published in: Mediators of inflammation (2024)

Dysregulation of PLCG2 and IFNAR1 are key factors in disease occurrence and development of AS through regulating immune infiltration and osteoclast differentiation. Explaining the differences in immune infiltration and osteoclast differentiation between AS and normal samples will contribute to understanding the development of spondyloarthritis.

Keyphrases

ankylosing spondylitis
peripheral blood
disease activity
bone loss
rheumatoid arthritis
risk assessment