Cross-sectional study on exhaled nitric oxide in relation to upper airway inflammatory disorders with regard to asthma and perennial sensitization.
Christina KrantzSimone AccordiniKjell AlvingAngelo G CorsicoPascal DemolyDiogenes S FerreiraBertil ForsbergJudith Garcia-AymerichThorarinn GislasonJoachim HeinrichRain JõgiAne JohannessenBénédicte LeynaertAlessandro MarconJesús Martínez-Moratalla RoviraElisabet NerpinDennis NowakAnna-Carin OlinMario OlivieriAntonio Pereira-VegaChantal Raherison-SemjenFrancisco Gómez RealTorben SigsgaardGuilia SquillaciotiChrister JanssonMalinovschi Andreinull nullPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)
Current rhinitis and rhinoconjunctivitis was associated with higher FeNO, with an interaction with perennial sensitization. This further highlights the concept of united airway disease, with correlations between symptoms and inflammation in the upper and lower airways and that sensitization needs to be accounted for in the relation between FeNO and rhinitis.