Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation.

Juying JiaoLinjie RuanChien-Shan ChengFengjiao WangPeiwen YangZhen Chen

Published in: Molecular medicine (Cambridge, Mass.) (2023)

Paired protein kinases PRKCI-RIPK2 with multiple phosphorylation activities represent a new pathological mechanism in PC and could provide potential targets for PC therapy.

Keyphrases

signaling pathway
pi k akt
protein protein
amino acid
cell death
oxidative stress
binding protein
protein kinase
stem cells
cell proliferation
lps induced
risk assessment
mesenchymal stem cells
immune response
bone marrow
cell therapy
endoplasmic reticulum stress