Three rounds of a national external quality assessment reveal a link between disharmonic anti-SARS-CoV-2 antibody quantifications and the infection stage.
Christoph BuchtaDavid Niklas SpringerJovana JovanovicChristian BorsodiLisa WeidnerNazanin SarebanUlla RadlerMathias M MüllerAndrea GriesmacherElisabeth Puchhammer-StöcklThomas WagnerChristof JungbauerKarin StiasnyLukas WeseslindtnerPublished in: Clinical chemistry and laboratory medicine (2023)
Measured BAU/mL levels are only inter-changeable among different laboratories when the same assay was used for their assessment. Highly variable ratios of BAU/mL quantifications among different immunoassays and infection stages argue against the usage of universal inter-assay conversion factors.