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Impact of Elexacaftor-Tezacaftor-Ivacaftor on Bacterial Colonization and Inflammatory Responses in Cystic Fibrosis.

Shahid I SheikhRodney D BrittNancy A Ryan-WengerAiman Q KhanBrandon W LewisCourtney GushueHazel OzunaDevi JaganathanKaren S McCoyBenjamin T Kopp
Published in: Pediatric pulmonology (2022)
In pwCF, ETI significantly improved clinical outcomes, reduced systemic pro-inflammatory cytokines, and restored circulating immune cell composition after 6 months of therapy. This article is protected by copyright. All rights reserved.
Keyphrases
  • cystic fibrosis
  • pseudomonas aeruginosa
  • lung function
  • anti inflammatory
  • chronic obstructive pulmonary disease
  • bone marrow
  • air pollution