TNF promoter hypomethylation is associated with mucosal inflammation in IBD and anti-TNF response.

Daniel S LevicDonna NiedzwieckiApoorva KandakatlaNorah S KarlovichArjun JunejaJieun ParkChristina StolarchukShanté AdamsJason R WillerMatthew R SchanerGrace LianCaroline BeasleyLindsay MarjoramAnn D FlynnJohn F ValentineJane E OnkenShehzad Z SheikhErica E DavisKimberley J EvasonKatherine S GarmanMichel Bagnat

Published in: medRxiv : the preprint server for health sciences (2024)

promoter methylation analysis may aid in the characterization of IBD status and evaluation of anti-TNF therapy response.

Keyphrases

rheumatoid arthritis
dna methylation
ulcerative colitis
gene expression
transcription factor
oxidative stress
genome wide
stem cells
cell therapy